Smartphone-based high-performance Thin Layer Chromatographic Method Along with Benchtop Densitometry for Simultaneous Quantification of Co-formulated Dutasteride with Silodosin and Their Residuals on Manufacturing Equipment's Surfaces

Mina Wadie, Analytical Chemistry Department, Faculty of Pharmacy - Cairo University, Kasr El-Aini Street, ET-11562, Cairo - EgyptFollow
Ezzat M. Abdel-Moety, Analytical Chemistry Department, Faculty of Pharmacy - Cairo University, Kasr El-Aini Street, ET-11562, Cairo - Egypt
Mamdouh R. Rezk, Analytical Chemistry Department, Faculty of Pharmacy - Cairo University, Kasr El-Aini Street, ET-11562, Cairo - Egypt.
Hoda M. Marzouk, Analytical Chemistry Department, Faculty of Pharmacy - Cairo University, Kasr El-Aini Street, ET-11562, Cairo - Egypt.

Subject Area

General Chemistry

Abstract

The significant advancement in smartphone digital cameras has expanded the possibilities for their usage as a portable, easily used detector in several analytical procedures. In this study, a unique and smart high-performance thin layer chromatographic (HPTLC) method based on a smartphone was presented for the simultaneous analysis of silodosin and dutasteride, two urological medications used to treat benign prostatic hyperplasia.First, environmentally friendly mobile phase was used to achieve chromatographic separation, and for repeatable findings, the produced plates were shot using the back camera of smartphone mounted atop a made-up twoillumination source chamber.

Recommended Citation

Wadie, Mina; Abdel-Moety, Ezzat M.; Rezk, Mamdouh R.; and Marzouk, Hoda M. (2023) "Smartphone-based high-performance Thin Layer Chromatographic Method Along with Benchtop Densitometry for Simultaneous Quantification of Co-formulated Dutasteride with Silodosin and Their Residuals on Manufacturing Equipment's Surfaces," Bulletin of Faculty of Pharmacy Cairo University: Vol. 61 : Iss. 1 , Article 4.
Available at: https://doi.org/10.54634/2090-9101.1040